Isıtılmış Tütün Ürünü İlişkili Subakut Akciğer Hasarı

Abstract

Heated tobacco products release nicotine without burning tobacco with an electronically controlled heating system. 56-year-old male patient admitted with sudden onset of chest pain and shortness of breath. He had been using a heated tobacco product (I quit ordinary smoking, IQOS) for 2.5 years. Thoracic computed tomography scan revealed pleural-based atelectasis and fibroatelectatic changes in the lower lobe of the right lung, pleural fluid in the right upper lobe, fibroatelectatic changes and pleural thickening in the left lung. Biopsy taken with video-assisted thoracic surgery (VATS) showed lymphoid aggregation in nodular form and widespread anthracosis around the lung, fibrillar material that double-refracting the light in the alveoli, hyaline membrane-like material in the alveoli, type 2 pneumocyte hyperplasia, an interstitial organization, and a subacute lung injury picture with exogenous lipoid material. These findings were evaluated in accordance with toxic substance-induced chemical pneumonia. It was thought that it might be related to 2.5 years of using heated tobacco product.