Abstract

COVER PHOTOGRAPH: Tbx4+/Cre mice were bred with R26mT/mG reporter mice to determine the activity of the recombinase in lung. The double‐fluorescent R26mT/mG reporter mouse line expresses the membrane‐targeted tandem dimer Tomato (mT) prior Cre‐mediated excision and membrane‐targeted enhanced green fluorescent protein (mG) after excision. At E12.5, EGFP expression was restricted to the respiratory tract mesenchyme while the surrounding tissues remained Tomato‐positive in R26+/mTmG;Tbx4+/Cre specimens. From Lung development requires an active ERK/MAPK pathway in the lung mesenchyme, Olivier Boucherat, Kim Landry‐Truchon, Rifdat Aoidi, Nicolas Houde, Valérie Nadeau, Jean Charron, and Lucie Jeannotte, Developmental Dynamics 246:72‐82.Read the full article at DOI: 10.1002/dvdy.24464

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