Abstract
Cover Photograph:Upper left: Simultaneous induction of ureagenesis and gluconeogenesis coincides with a corticosterone surge occurring prior to metamorphosis in Xenopus laevis (see Konno, pp. 6–15). Upper right: Transverse sections of the tibiofibula at Gosner stage 42 (top panels), of Xenopus tropicalis (left) and Ceratophrys cranwelli (right); Ca: cartilage, CB: cortical bone, Mu: muscle. Bottom panels show adult frogs (see Kondo et al. pp. 16–22).Lower left: Maea knockdown interferes with head formation. Wild type (top) and morphant phenotypes with small eyes (middle) and no eyes (bottom) are shown (see Goto et al. pp. 29–36).Lower right: ChIP‐seq analyses of target genes of thyroid hormone receptors (TR) in tail, hindlimb and intestine in tadpoles during Xenopus metamorphosis. Venn diagrams show much fewer TR‐bound genes in TRa‐knockout X. tropicalis frogs compared to wild type (see Tanizaki et al. pp. 23–28).image
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