Abstract
Front cover: The node forming transiently in mammalian embryos plays a key role in left‐right axis determination. The node is a cavity, in which crown cells with immotile cilia surround pit cells that rotate their motile cilia to generate a leftward fl uid fl ow (nodal fl ow). Experiments using GCaMP6, which emits green fl uorescence in response to Ca2+, and optical tweezers revealed that immotile cilia sense mechanical force generated by nodal fl ow (Katoh et al. (2023) Science 379: 66–71, DOI: 10.1126/science.abq8148). A similar mechanism was shown to exist in zebrafi sh (Djenoune et al. (2023) Science 379: 71–78, DOI: 10.1126/science.abq7317). This picture shows the application of this mechanism to ‘hiburi‐ryo’ (fishing by using flames to drive fish). The fishermen in the pond are creating a leftward current to be sensed by the men on the left bank, who are activated, and their torch flames intensify. Designed by TRAIS Co., Ltd. (Kobe, Japan).image
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
