Issue Highlights

Abstract

BioFactorsVolume 48, Issue 1 p. 6-6 ISSUE HIGHLIGHTSFree Access Issue Highlights First published: 03 February 2022 https://doi.org/10.1002/biof.1737AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Ginger and its constituents: Role in treatment of inflammatory bowel disease Naser-Aldin Lashgari,Nazanin Momeni Roudsari,Danial Khayatan,Maryam Shayan,Saeideh Momtaz,Basil D. Roufogalis,Amir Hossein Abdolghaffari,Amirhossein Sahebka Inflammatory bowel diseases are rising and are of worldwide concern. Ginger (the rhizome of Zingiber officinale) has a broad spectrum of clinical applications due to its anti-inflammatory and anti-oxidative functions. Inflammation and oxidative stress are the key pathogenic factors in many diseases, including IBD. The anti-inflammatory activity of ginger has been documented by many researchers. Ginger is a potent inhibitor of NF-κB, STATs, NLRPs, TLRs, MAPKs, and mTOR pathways, as well as inhibiting various pro-inflammatory cytokines. In this report, the potential application of ginger and its bioactive components in the management of IBD is reviewed in detail. 7 Dioscin: A review on pharmacological properties and therapeutic values Shinjini Bandopadhyay,Uttpal Anand,Vijaykumar Shivaji Gadekar,Niraj Kumar Jha,Piyush Kumar Gupta,Tapan Behl,Manoj Kumar, Radha,Mahipal S. Shekhawat,Abhijit Dey Dioscin, one bioactive compound found in some medicinal plants has acquired significant attention as a natural, bioactive pleiotropic saponin with immense pharmacological and therapeutic potential to treat a plethora of diseases. Undoubtedly, dioscin's outstanding protective effects against several human cancers, liver, stomach and intestine damages, kidney, brain, metabolic disorders (osteoporosis, hyperuricemia, diabetes, obesity), organ damage, and fungal/viral infections through the modulation of various targets and signals have been revealed in recent investigations. As a result, dioscin appears to be a promising multi-target drug candidate for treating a variety of disorders and is considered to be a magic bullet. 22 REFERENCES 1Naser-Aldin Lashgari, Nazanin Momeni Roudsari, Danial Khayatan, Maryam Shayan, Saeideh Momtaz, Basil D. Roufogalis, Amir Hossein Abdolghaffari and Amirhossein Sahebka. Ginger and its constituents: Role in treatment of inflammatory bowel disease. BioFactors. 2022; 48: 7– 21. Google Scholar 2Shinjini Bandopadhyay, Uttpal Anand, Vijaykumar Shivaji Gadekar, Niraj Kumar Jha, Piyush Kumar Gupta, Tapan Behl, Manoj Kumar, Radha, Mahipal S. Shekhawat and Abhijit Dey. Dioscin: A review on pharmacological properties and therapeutic values. BioFactors. 2022; 48: 22– 55. Google Scholar Volume48, Issue1January/February 2022Pages 6-6 ReferencesRelatedInformation