Issue Highlights

Abstract

The Canadian Journal of Chemical EngineeringVolume 97, Issue 10 p. 2575-2575 Issue HighlightsFree Access Issue Highlights First published: 12 September 2019 https://doi.org/10.1002/cjce.23281AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Experimental methods in chemical engineering: Micro-reactors-p. 2578 Arturo Macchi, Patrick Plouffe, Gregory S. Patience and Dominique M. Roberge The bulk chemical industry continues to build bigger plants but micro-reactors represent a paradigm shift in manufacturing: they contribute to process intensification—productivity an order of magnitude (and more) greater in a smaller footprint—with sub-millimetre lateral dimensions that reduce heat and mass transfer boundary layers. We propose a toolbox concept to select reactor types in order to optimize reactive conditions and then scale up, with relative confidence, through the clinical phases of pharmaceuticals. Research in the field is concentrated into five clusters: catalysis and kinetics; nano-particles; systems and microfluidics; chemistry and organic synthesis; and mass transfer and micro-channels.1 Experimental methods in chemical engineering: X-ray photoelectron spectroscopy-XPS-p. 2588 Josianne Lefebvre, Federico Galli, Claudia L. Bianchi, Gregory S. Patience and Daria C. Boffito X-ray photoelectron spectroscopy (XPS) identifies the elemental composition, empirical formula, chemical state, and electronic state of solid surfaces to a depth of 1-10 nm. With an atomic sensitivity of 0.1%, any exposure to ambient air contaminates the surface. X-ray beams irradiate solids held at 0.1 μPa and produce spectra of electrons where the intensity relates to concentration and position to an element's orbital and chemical environment. Research clusters that apply the technique include: nanoparticles and thin films; catalysis and oxidation; nanocomposites and graphene; photocatalysis and TiO2; and adsorption and aqueous solutions.2 Functionalized bacterial cellulose nanowhiskers as long-lasting drug nanocarrier for antibiotics and anticancer drugs-p. 2594 Mohamed M. Khattab and Yaser Dahman Biocompatible and nontoxic drug-nanocarriers based on a functionalized bacterial cellulose nanowhisker (BCNC-g-βCD) were developed. Compared to a pristine nanowhisker, the obtained drug-nanocarriers showed promising potential for conjugating higher payloads of antibiotic and anticancer drugs ranging from 495 ± 14 to 810 ± 17 μg/mg. In addition, the drug release profiles showed that 75-90% of drug payloads were released over 5-5.5 days in sustained and controlled manners with reduced initial blasts. Moreover, promoted drug release profiles were pragmatic in an acidic pH of 6.4 at 37°C, which mimics the tumour environment. The obtained observations demonstrate versatile medical applications for the obtained nanocarriers in localized and long-lasting drug delivery.3 Impeller power draw during turbulent operation in solid-liquid suspensions-p. 2662 Kevin J. Myers, Eric E. Janz, Tianxin Bao and M. Molly Heigel Measurements with six impeller types in solid-liquid suspensions indicate that power draw in the turbulent regime is approximately proportional to suspension density when the solids are distributed throughout the liquid; however, the accuracy of this approach is limited, with clear differences between impellers. Power draw increases are less than density increases for impellers with large blade-trailing vortices and are equal to or greater than density increases for impellers with smaller blade-trailing vortices. The data is well described by linear relations between impeller power number and the density difference correlating parameter of Micheletti et al, with slope depending on impeller type.4 REFERENCES 1A. Macchi, P. Plouffe, G. S. Patience, D. M. Roberge, Can. J. Chem. Eng. 2019, 97, 2578. 2J. Lefebvre, F. Galli, C. L. Bianchi, G. S. Patience, D. C. Boffito, Can. J. Chem. Eng. 2019, 97, 2588. 3M. M. Khattab, Y. Dahman, Can. J. Chem. Eng. 2019, 97, 2594. 4K. J. Myers, E. E. Janz, T. Bao, M. M. Heigel, Can. J. Chem. Eng. 2019, 97, 2662. Volume97, Issue10October 2019Pages 2575-2575 ReferencesRelatedInformation