Abstract
Cover legend: Dengue virus capsid protein accumulates around lipid droplets during infection. Dengue viruses cause the most important human viral disease transmitted by mosquitoes. We have investigated the host machinery necessary for viral capsid protein transport from ER membranes to lipid droplets. Our results support a model in which the virus uses a non-canonical function of the GBF1-Arf1/Arf4-COPI system for capsid accumulation on lipid droplets. Cover: dengue virus infected cells showing lipid droplets stained with BODIPY (green) and co-localization between the host lipid droplet-associated protein TIP47 (blue) and the viral capsid protein (red). See Iglesias et al. Traffic 2016; 16(9):962–977. Read the full article on doi:10.1111/tra.12305
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