Abstract
Front cover: The photomicrographs show both the co-localization of the glioblastoma tumor suppressor neurofibromin with mitotic microtubules and normally congressed chromosomes at metaphase in astrocytes. Neurofibromin depletion leads to aberrant chromosome congression, a possible mechanism for the generation of CIN/aneuploidy in neurofibromatosis patients who have a 5-fold increase incidence of glioblastoma. Read the full article ‘Nuclear import mechanism of neurofibromin for localization on the spindle and function in chromosome congression’ by X. Koliou, C. Fedonidis, T. Kalpachidou and D. Mangoura (J. Neurochem. 2016, vol. 136 (1), pp. 78–91) on doi: 10.1111/jnc.13401
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