Abstract
Front cover: Rat spinal cord oligodendrocytes differentiating in vitro. A pure oligodendroglial lineage cell (OLC) culture from the rat neonatal spinal cord is stained for oligodendrocyte markers, O4 antigen (red) and galactocerebroside (green) by immunocytochemistry. Nuclei are stained with DAPI (Blue). By comparing pure oligodendrocyte cultures from rat spinal cords and forebrains, we demonstrated differing intrinsic biological properties between these two OLC groups originated from distinct CNS regions. Further understanding the regional differences of oligodendrocytes will help to improve treatments for demyelination in different CNS regions and to facilitate the development of stem cell-derived OLCs for cell transplantation therapies for demyelination. Read the full article ‘Differing intrinsic biological properties between forebrain and spinal oligodendroglial lineage cells’ by M. Horiuchi, Y. Suzuki-Horiuchi, T. Akiyama, A. Itoh, D. Pleasure, E. Carstens and T. Itoh (J. Neurochem. 2017, vol. 142 (3), pp. 378–391) on doi: 10.1111/jnc.14074
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
