Ispitivanje povezanosti težine srca sa rupturom srca kod 119 slučajeva umrlih od akutnog infarkta miokarda

Abstract

Introduction. Cardiovascular and blood vessel diseases are the most common cause of death, which is shown by data obtained in our and foreign authors' research, and acute myocardial infarction is the most common emergency in internal medicine and its mortality is very high, about one third of total mortality. The aim of this paper is to determine whether there is a statistically significant difference in heart weight in deceased patients with acute myocardial infarction (AMI) with heart rupture and with AMI without heart rupture. Methods. The research material is made up of 119 autopsied patients at the Institute of Pathology of the University of Kragujevac Medical Faculty and Clinical Center Kragujevac. The following pathological morphological research methods were applied: autopsy, macroscopic diagnostics and microscopic analysis. In addition, a statistical processing of results was performed, and the Pharmocologic Circulapon System Student's t-test statistical software package was used to test the significance of differences. A value of p<0.05 was considered as a statistically significant difference, and a value of p<0.01 as highly significant. Results and Discussion. Out of 119 cases of AMI deaths, of which 74 male and 45 female, heart rupture was found in 21 cases. Of the 74 men who died of AMI, 13 had a rupture, and of the 45 women who died of AMI, 8 had a rupture. The heart weight was measured in each respondent who died of AMI and the correlation between heart weight and rupture was investigated. The study showed that there was a statistically significant difference (p<0.05) in the average heart weight between the autopsied who had and those who did not have heart rupture, and that those who did not have heart rupture had significantly more heart weight. The study showed that there was a statistically significant difference (p<0.05) in the average heart weight between the autopsied men who had and those who did not have heart rupture. The heart of those men who did not have heart rupture had more weight. There were no statistically significant differences (p>0.05) in the mean heart weight between the autopsied women who had and those who did not have heart rupture. Conclusion. The study showed the difference in the heart weight of autopsied patients who had and those who did not have heart rupture, and that those who did not have heart rupture had significantly more heart weight. In relation to sex, the heart of those men who did not have heart rupture had more weight, while in women there are no statistically significant differences (p>0.05) in the average heart weight in those with and without rupture of the heart.