Abstract
Crystalline and consequently isoporous bacterial cell surface layers (S-layers) which are composed of a single protein or glycoprotein species have been employed for the preparation of ultrafiltration membranes. So far channels of 2-6 nm diameter have been identified in S-layer lattices. Their porosity ranges from 20 to 50%. S-layer ultrafiltration membranes (SUM) are produced through deposition of S-layer material on microfiltration membranes, which is followed by crosslinking the S-layer protomers. SUM display steep rejection curves and show the potential to fractionate protein mixtures. Moreover, they are rather resistant towards acid, alkali and organic solvents.
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