Abstract

Isoniazid is effective in preventing tuberculous complications, thus minimizing the danger of primary tuberculosis. Isoniazid is a remarkably effective agent for the treatment of all clinical forms of tuberculosis in children. Since effective therapy is now available, every effort should be made to seek out the infected children by routine tuberculin testing so that they may receive the benefit of INH therapy in the early stage of the infection. Special attention should be given to children under 36 months of age because of the high mortality and morbidity rates of tuberculosis at this age period. In countries where tuberculosis incidence is low and where BCG vaccine is not in general use, routine tuberculin testing of young children serves the dual-purpose of early treatment of primary tuberculosis in children and the detection of unrecognized tuberculosis in adults.

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