Abstract
Sericin is a silk worm secreting protein occurring naturally as a silk cocoon.It is a typical example of a natural core-shell structure. Silk cocoon constitutes about 75% of core silk fibroin (SF) and 25% of shell silk sericin (SS). Silk fibroin has a potential application in the textile and biomedical field due to its inherent mechanical strength. Sericin is a hydrophilic protein that has a greater affinity with silk fibroin;hence it binds with silk fibroin coaxially to protect pupa from predators, temperature variations, moisture, mechanical abrasions, etc.. During the commercial production of raw silk fiber, sericin will be degummed by treating the cocoon with hot water at high temperatures and discharged as wastewater after extraction of silk fibroin from cocoons. Sericin protein posse’s potential application in the field of cosmetics as an additive in skin moisturizer, shampoo, anti-wrinkle creams due to the presence of hydroxyl amino acids, wound healing, promoting cell growth and differentiation in pharmaceutical industries due to its biological origin without causing an undesirable immunological response. Sericin protein was extracted from discharge water collected from the silk industry was purified and characterized using SDS-PAGE, FTIR, CD, SEM, DSC & TG-DTA was reported.
Highlights
Sericin is a natural hydrophilic protein derived from silk worm
(14- 2 of seri extraction (Khan et al, 201807),s. lSoaodaepd aanlodngawlkitahliloading sbtuaffienreidn wthiethlacnoeo: m2.aInssstireumbreinlltiaTnhtebinlusterusmoeluntioisnaflolorw2ed to run at 100V fo extraction (Rajkhowa et a8l8., 20h1ou1r).,Geenl wzyams raetciocvaelred and hstoauinresdawnitdh rcionosmeadsswieitbhridlliiasnttillbeludewsoaltuetiro.nGfeorl 2whaosudrsea-nd rinsed with distil extraction (Gulrajani et al, 280900)waantderH
Purified, and characterize9d1from discharge water collected from a silk reeling92unit
Summary
Sericin is a natural hydrophilic protein derived from silk worm. Sericin has a potential application in skin moisturizer due to high content of hydroxyl amino acids and its anti-wrinkle action (Engel et al, 1987). INTRODUCTION: Sericin is a natural hydrophilic protein derived from silk worm. Purification of sericin can be achieved using different available methods, namely, Results & Discussion: Characterization of sericin protein: SDS- PAGE analysis: (oaf)h. High-Range-2 Protein Mar9k7er (14- 220 kDa) was purchased from SRL chemicals (Cat No: 99625).
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