Abstract
We have induced teratocarcinomas in C3H He strain mice by extra-uterine transplantation of egg cylinder stage embryos. Embryonal carcinoma cell lines with male karyotypes were isolated from three different tumor lines. One of the cell lines has a normal karyotype. The Y chromosome in each of two lines tested replicates late during the S phase of the cell cycle at the same time as Y chromosomes in male somatic cells.
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