Abstract

Isolation of Kojic Acid Producing Mold using Complex Carbon Sources

Highlights

  • An independent effort in term of pharmaceutical raw materials procurement in Indonesia, especially skin brightening agent, is required due to the high demand of brightening skin care product

  • Kojic acid is one of the skin brightening agent widely used in cosmetic skincare formulations

  • Kojic acid is a major secondary metabolite produced by mold such as Aspergillus and Penicillium species.[3,4,5]

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Summary

Introduction

An independent effort in term of pharmaceutical raw materials procurement in Indonesia, especially skin brightening agent, is required due to the high demand of brightening skin care product. One of the skin brightening agent widely used in cosmetic skin care formulations is kojic acid. Skin Care Products are the first Best Cosmetic Sales Prospects in Indonesia, including brightening products.[1] This fact leads the high demand pharmaceutical raw materials such as brightening agents are required. 90% of pharmaceutical raw material in Indonesia are still imported.[2] an independent effort in term of the raw materials procurement in Indonesia’s pharmaceutical industry, especially skin brightening agent, is required. Kojic acid is one of the skin brightening agent widely used in cosmetic skincare formulations. Kojic acid is a major secondary metabolite produced by mold such as Aspergillus and Penicillium species.[3,4,5] Glucose, sucrose, acetate, ethanol, arabinose, and xylose have been used as carbon sources for kojic acid production.[6,7]

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