Isolation of hypoxoside from hypoxis rooperi and synthesis of (E)-1,5-bis(3′,4′-dimethoxyphenyl)pent-4-en-1-yne

Abstract

Isolation of the known diglucoside of (E)-1,5-bis(3′,4′-dihydroxyphenyl)pent-4-en-1-yne (hypoxoside) from Hypoxis rooperi is described. In vivo tests indicate low toxic properties. A general synthesis for the introduction of the pentenyne link between two aromatic rings is described.