Abstract
Insolubilized fibrinmonomer, which is converted from insolubilized fibrinogen by thrombin action, adsorbs soluble fibrinogen from solutions or plasma. After treatment with 6 molar urea without removal of the fibrinopeptides insolubilized fibrinogen gets a high affinity for soluble fibrinogen, too. Insolubilized fibrinmonomer and urea-treated insolubilized fibrinogen are suitable adsorbents for the purification of fibrinogen from plasma by affinity chromatography.
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