Abstract
Rhaphiostylis beninensis is used in traditional medicine in Nigeria as an anti-inflammatory crude drug. This claim was investigated through bioactivity- guided fractionation chromatography using the Carageenan induced Rat Paw inflammation model. A sulphonyl derivative: N,N -Bis [ (4-methoxyphenyl) methyl]thiourea was isolated and it's structure was elucidated using Mass Spectrometr and Nuclear Magnetic Resonance (HNMR and 13CNMR). The anti-inflammatory activities were enhanced with fractionation and subsequent chromatographic exercises. The occurance and anti-inflammatory activity of the compound are reported for the first time in Rhaphiostylis beninensis. The results confirm the traditional use of the plant.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
