Abstract
A 14-membered macrolide, koshikalide ( 1), was isolated from the marine cyanobacterium Lyngbya sp., and its planar structure was elucidated by spectroscopic analysis. The relative stereochemistry of C-11 and C-13 was elucidated by NOESY experiments and by an analysis of 1H– 1H coupling constants. Koshikalide ( 1) exhibited weak cytotoxicity against HeLa S 3 cells.
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