Isolation and Structure Elucidation of Secondary Metabolites from the Roots of the Tunisian Convolvulus dorycnium

Abstract

A phytochemical investigation of the roots of Convolvulus dorycnium led to the isolation of a new phenolic metabolite methyl 3-(3-caffeoyl-1,2-dihydroxycyclobutyl)-3-hydroxypropanoate (1) named convoldorine and the previously known dorycnic acid (2), chlorogenic acid (3), scopolin (4) and scopolitin (5). Their structures were elucidated on the basis of spectroscopic evidence, including 1D and 2D NMR experiments and by comparison with authentic samples.