Abstract
The plant, Centaurea perrottetii DC (Asteraceae) is a herbaceous thistle-like shrub used in traditional medicine for the treatment of malaria, fever, syphilis, ulcer and skin infections. The aim of the study is to isolate and elucidate the structure of compound(s) from C. perrottetii. Quercetin-derivative (an amino-flavone) was isolated from the n-hexane fraction of the methanol extract of the whole plant of Centaurea perrottetii using a combination of silica gel column and gel filtration chromatography. The structure of the compound as 2-(3,4-dihydroxyphenyl)-3-((1-ethylcyclopropyl)amino)-5,7-dihydroxy-4Hchromen-4-one was established via chemical tests, Ultraviolet (UV), Infrared (IR), 1D- and 2D-dimensional NMR spectroscopy. This is the first report of isolation of this compound from Centaurea perrottetii.
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