Isolation and Selective Drug of Chose for Pseudomonas Aeruginosa as a Causative Agent in Suppurative Otitis Media

Abstract

Background: Chronic Suppurative otitis media (CSOM),is a chronic inflammation of the middle ear andmastoid cavity, which presents with recurrent (otorrhea) ear discharge through a perforated tympanicmembrane. The bacterial cause for CSOM can include both aerobic and anaerobic bacteria ,the most commonmicroorganisms found in CSOM are Pseudomonas aeruginosa, Staphylococcus aureus, Proteus mirabilis,Klebseilla pneumonia , diphtheroid group, Citrobacter sp. and anaerobic bacteria and fungi like Candida spas well asAspergillus sp.P. aeruginosa was the most common iso 30500000) fallowed by S.aurease 27% (27 isolates) , Proteusmirabilis 11% (11 isolates),E.Coli 11%(11 isolates), Klebseilla pneumonia 9 %(9 isolates), respectivelywhile other different species was 5% (5 isolates) and 2% (2 isolates) was fungi. Antimicrobial sensitivityfor P. aeruginosa test by VITEK 2 System based on the main inhibitor concentration (MIC).The Piperacillinshowed to be highly sensitive again P. aeruginosa 77.1% (27 isolation ) followed by Meropenem , Imipenem,Levofloxacin and Amikacin 65.7% (23 isolation), 60%(21 isolation), 40%(14 isolation), 34.2%(12isolation) respectively while Ciprofloxacin showed to be the les effected again P. aeruginosa 20% (7isolation). Ceftazidime , Tobramycin and Ciprofloxacin were highly resistance 68.5% (24isolation). 62.8%(22 isolation) . 54.2%(19 isolation) respectively.