Isolation and partial characterization of an histidine-rich polypeptide from parotid saliva of the monkey, Macaca nemestrina

Abstract

1. 1. An histidine-rich polypeptide has been isolated from the parotid saliva of Macaca nemestrina by column Chromatographic methods and compared to a similar molecule from human parotid saliva. 2. 2. The fraction has been characterized by amino acid composition, molecular weight, electrophoretic behavior, ultra violet absorption and circular dichroic spectra. 3. 3. The pattern of appearance in saliva suggests the histidine-rich polypeptide is a secretory molecule. 4. 4. Additional histidine-rich polypeptides observed in saliva are probably degradation products of this fraction.