Abstract
Abstract: Klebsiella pneumoniae, an important multi drug resistant opportunistic pathogen, it is able to colonise the human intestine and displays a high capacity to form biofilm; which are communities of bacteria embedded in an extracellular matrix. This matrix consists of proteins, exopolysaccharides, DNA, and lipopeptides. K. pneumoniae used these virulence factors for survival and for evade from immune system during infection as well as biofilm formation itself. Type1 and Type3 fimbriae produces biofilm. Biosurfactants produced by Lactobacilli has the ability to reduce adhesion of Klebsiella and inhibit biofilm formation. In this study antibiofilm activity of Lactobacillus was assessed against Klebsiella pneumoniae.
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