Abstract
Tapinanthus globiferus (A. Rich) Tiegh (Loranthacae) is a semi-parasitic plant growing on several plant species such as Vitex doniana. it is used in ethno-medicine for the treatment of fungal infection, itching, hypertension, ulcers, epilepsy, diabetes and cancer. The aim of this study was to isolate bioactive compound(s) from the leaf of T. globiferus. The powdered plant material was extracted with 90% methanol using maceration method and the resulting crude methanol leaf extract was partitioned into n-hexane, chloroform, ethylacetate and n-butanol fractions. The ethylacetate fraction was chromatographed on a silica gel and sephadex LH-20 column which led to the isolation of two flavonoids, and the identity of the compounds was determined on the basis of chemical test and NMR analysis. Based on the 1D and 2D NMR data, the compounds were 2-(3’4’-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromane-4-one (quercetin) and 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylhexyl)-4H-chromen-4-one. This is the first report of isolation of these compounds from T. globiferus growing on Vitex doniana.
Highlights
Ogunbolude et al (2014) reported the identification and quantification of quercetin and some phenolic acids from T. globiferus growing on other host
Extensive literature search revealed that there is no report yet on the isolation and characterization of any compound from the plant T. globiferus growing on Vitex doniana
The isolation and characterization of two flavonoids, quercetin and 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylhexyl)-4H-chromen-4-one from the leaf T. globiferus growing on Vitex doniana
Summary
Rich) Tiegh belonging to the Loranthaceae Family is a semi-parasite with glabrous pendulous stems up to 1.2 m long with roots that mostly grows on the branches of a large number of tree species including Vitellaria paradoxa, Kola, Citrus, Combretum, Acacia, Aloe and Terminalia as host trees (Waterberg et al, 1989; Polhill and Wiens, 1998). It is commonly known as mistletoe (English), Kauchi (Hausa), afomo (Yoruba), and Osisi/Okwuma osa (Igbo) in Nigeria. Extensive literature search revealed that there is no report yet on the isolation and characterization of any compound from the plant T. globiferus growing on Vitex doniana
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