Abstract

Antibiotics are antimicrobial drugs that kill germs and are crucial in the fight against bacterial infections. These medications are widely used in the prevention and treatment of diseases because they may either kill or stop bacteria from growing. Microbial resistance refers to bacteria's capacity to survive antibiotics' bacteriostatic or cytotoxic effects. The samples for this study are taken from Song and Suswa River, Dehradun, Uttarakhand. The main aim of this study is to isolate several species to find out if them are resistant to antibiotics. The methodologies used in this research are isolation and haracterization of bacteria, antibiotics sensitivity test. There were 17 types of antibiotics were used i.e. Azithromycin, Amikacin, Cefaclor, Cefepime, Cefoxitin, Doxycycline Hydrochloride,Erythromycin, Gentamycin, Kanamycin, Levofloxacin, Mecillinam, Mezolocilline, Penicillin G, Vancomycin, Tetracycline, Ticarcilline, Nitrofurantoin. The result was that species like Salmonella, Pseudomonas, E. coli, Klebsiella were resistant, sensitive, and intermediate against the 17 antibiotics. Antibiotic-resistant bacteria can potentially be transferred from one to another in a society. This is gradually getting frequent these days. In short, antibiotic resistance cannot be prevented or, in some cases, reversed, but we can certainly slow its progression.

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