Isolation and characterization of dipropyl-, S-propyl ester from Exiguobacterium mexicanum (MSSRF-S9) against larvae of malaria and dengue vectors

Abstract

ObjectiveTo evaluate the insecticidal property of the compound dipropyl-, S-propyl ester extracted from the Gram-positive rhizosphere bacterium against the fourth instars larvae of malaria vector, Anopheles culicifacies (An. culicifacies) and dengue vector, Aedes albopictus (Ae. albopictus). MethodsBacteria were taxonomically identified as Exiguobacterium mexicanum (E. mexicanum) and different crude solvent extracts were examined for its larvicidal potential against mosquito vectors. The crude extract was eluted in silica gel column chromatography and the pure compound was identified. ResultsThe highest larvicidal activity against An. culicifacies was exhibited by ethyl acetate extract. The bacterium of E. mexicanum extract at 150, 300, 450, 600, 750 mg/L caused against both vector mosquito species. Hexane, chloroform, acetone, methanol and ethyl acetate caused moderate considerable mortality. The highest larval mortality was observed in ethyl acetate extract. ConclusionsThe results of the bacterial extract of E. mexicanum are promising as potential larvicidal compound against the mosquito vectors (An. culicifacies and Ae. albopictus). Therefore, this study provides first report on the larvicidal activity with dipropyl-, S-propyl ester compound from India.