Abstract
The presence of actively synthetized immunoglobulin in the serum of newborn precolostral germfree piglets was confirmed. This immunoglobulin, being of IgG antigenic type, carries determinants of typical IgG heavy and light chains and has a sedimentation constant of 4S. The first antibodies formed in germfree piglets after immunization with sheep red blood cells are of macroglobulinemic (IgM) nature. They are followed by formation of more slowly sedimenting antibodies of the IgG type. No fast sedimenting antibodies of the IgG type were detected.
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