Abstract

Abstract Given a finite set of n items, containing at least one defective item, and, for each item, the probability that it is defective, it is desired to determine a group-testing procedure which isolates a single defective with a minimum expected number of tests. We prove that such an optimal procedure can be found by constructing an optimal “alphabetic binary tree” for a derived set of weights obtained directly from the given probabilities. The algorithm for constructing the optimal procedure requires a number of operations proportional only to n log n.

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