Isolated Uterine Cervix Plasmacytoma Treatment Conundrum

Abstract

Solitary plasmacytoma is a type of plasma cell tumour that can either be present in the bone marrow as a Solitary Bone Plasmacytoma (SBP) or the soft tissue as an ExtraMedullary Plasmacytoma (EMP). In the case of both the distinction from other plasma cell dyscrasias such as multiple myeloma is based upon clinical, serological, histological and radiological studies. Solitary plasmacytoma is rare and accounts for 3-5% of all plasma cell malignancies [1]. They occur more in men than women (65% to 35%) with a median age of 55 years [2]. The axial skeleton is the most common site of SBP. However, if the plasmacytoma is an EMP approximately 85% of these lesions occur in the head and neck mucosa. We present a case of solitary extramedullary plasmacytoma confined to the cervix resulting in significant therapeutic and management implications owing to this unusual site of disease.