Isolated Splenic Tuberculosis without Any Radiological Focal Lesion.

Sunil Raviraj,A Kakar,S P Byotra,A Gogia

doi:10.1155/2015/130209

Abstract

Incidence of tuberculosis (TB) of spleen is a rare entity and isolated splenic tuberculosis is an unusual phenomenon, especially in immunocompetent individuals. We came across a case of 63-year-old male who presented with high grade fever, loss of weight, and generalized weakness of one-month duration. When physically examined, he had pallor and moderate nontender splenomegaly without any other significant clinical findings. He had pancytopenia, elevated ESR, and positive Mantoux test. Ultrasonography and CT scan of abdomen showed splenomegaly without any other relevant findings. Markers of connective tissue disorders and bone marrow aspiration and biopsy all were noncontributory for diagnosis. Hence splenic biopsy was done and sent for histopathological examination. Presence of caseation surrounded by epitheloid granulomas and Langerhans cells was suggestive of diagnosis as tuberculosis. And gene probe for the AFB (acid fast bacilli) came to be positive. No primary focus was present in either lungs or other organs. Patient improved clinically with antitubercular treatment.

Highlights

Tuberculosis is a bacterial infection which is caused by Mycobacterium tuberculosis
Splenic tuberculosis is exceptionally rare entity which usually occurs as a part of miliary tuberculosis and is more common in immunodeficient individuals
Tuberculosis is common infection caused by various strains of mycobacteria, most commonly by Mycobacterium tuberculosis

Summary

Introduction

Tuberculosis is a bacterial infection which is caused by Mycobacterium tuberculosis. In spite of early diagnostic and extensive treatment modalities the incidence of disease is still the major public health problem in developing countries [1]. While pulmonary tuberculosis is the most common manifestation, extra pulmonary disease accounts for approximately 15% of all tuberculosis [2]. Splenic tuberculosis is exceptionally rare entity which usually occurs as a part of miliary tuberculosis and is more common in immunodeficient individuals. We are reporting a case of splenic TB, as it is a rare entity

Case Report

Findings

Discussion