Abstract
Abstract Lomentaspora prolificans is a rare fungal infection that has emerged as an opportunistic pathogen, particularly in immunosuppressed patients. Infection can caused disseminated infection, as well as localized infections in multiple organs in the body, including the eye. Endophthalmitis is a sight-threatening condition most commonly caused by bacterial pathogens and rarely associated with fungal infection. Endophthalmitis caused by L. prolificans is typically the result of ocular penetration, active keratitis, or endogenous seeding with positive blood cultures. Infection with L. prolificans is very difficult to treat because of the limited efficacy of currently available antifungal medications. Thus, the prognosis of endophthalmitis secondary to L. prolificans is guarded. We present a case of a 70-year-old woman who developed isolated endophthalmitis from L. prolificans infection with no identifiable source.
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