Abstract
The common sites of relapses of acute lymphoblastic leukemia are bone marrow, central nervous system and testis. When unusual sites like eyes are involved in extramedullary relapses, they may masquerade as hypopyon uveitis. We report a child who presented with isolated hypoyon as an initial manifestation of Acute lymphoblastic relapse, 3 months after his completion of chemotherapy. Leukemic involvement of the anterior segment of the eye should be suspected in all cases of uveitis that are refractory to treatment and particularly when a hypopyon uveitis develops in a child.
Highlights
IntroductionThere has been considerable improvement in the survival rate of acute leukemic children [1]
With therapeutic advances, there has been considerable improvement in the survival rate of acute leukemic children [1]
There has been considerable improvement in the survival rate of acute leukemic children [1]. This has led to an increase in variability of ocular presentations in the form of side effects of treatment and leukemic relapses being first identified as an ocular presentation [2]
Summary
There has been considerable improvement in the survival rate of acute leukemic children [1] This has led to an increase in variability of ocular presentations in the form of side effects of treatment and leukemic relapses being first identified as an ocular presentation [2]. We report the case of 7 year old boy who completed his chemotherapy and presented with unilateral pseudohypopyon, few months later, which was subsequently diagnosed as relapse. He was treated with Children Oncology Group (COG) high risk ALL protocol. 3 months after his completion of treatment, he presented with redness, pain and photophobia in his left eye He was seen by an ophthalmologist and was being treated symptomatically with topical eye drops and analgesics. With the completion of induction phase of chemotherapy, the hyopyon resolved (fig 2) and bone marrow aspiration and CSF analysis showed no blasts. Pediatric Review: International Journal of Pediatric Research Available online at: www.pediatricreview.in 649 | P a g e
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