Isolated herpes simplex virus pneumonia in children

Abstract

Disseminated herpes simplex virus (HSV) infection is a well recognized condition in infants and children. However, the diagnosis of isolated HSV pneumonia, without evidence of other organ involvement, in this population is rare. We present a case series of isolated HSV pneumonia in four patients, all of which survived this acute illness with normal neurological outcome. Clinical features, diagnostic approaches, intensive care management, and antiviral drug therapy are reviewed.