Isolated flushes without permanent, fixed or other skin lesions in patients with systemic mastocytosis: a case series of 9 patients.

Abstract

Mastocytosis is a heterogeneous group of disorders characterized by abnormal growth and accumulation of mast cells (MCs) in one or more organ systems [1, 2]. Clinical manifestations of mastocytosis are related to the release of MC mediators or to pathological MC infiltration [1, 2]. Urticaria pigmentosa is present in almost 60% of cases of systemic mastocytosis [2-5].Flushing is a sensation of warmth accompanied by transient erythema, usually over the face, neck, ears, chest and limbs and is due [...]