Isolated Adenoma with Neuroendocrine Differentiation Involving Both the Facial Nerve and Parotid Gland

Ali K Mahrous,David A Moffat,Alison Marker,James R Tysome

doi:10.4236/ijohns.2014.32020

Abstract

Objective: To report an extremely rare case of neuroendocrine tumour with simultaneous involvement of both the facial nerve and the deep lobe of parotid gland. Method: case report and English language literature review concerning neuroendocrine neoplasm involving the facial nerve with emphasis on clinical presentation. Results: We report a unique case of adenoma with neuroendocrine differentiation which involved both the mastoid segment of the right facial nerve and also the deep lobe of the parotid gland on the ipsilateral side. Both tumours were not contiguous and were anatomically separate from each other. A CT scan of the whole body revealed no other neuroendocrine tumours. Conclusion: To the best of our knowledge, this is the first report in the English language literature of a neuroendocrine tumour to involve both the vertical mastoid segment of the facial nerve with simultaneous involvement of the deep lobe of parotid gland as a separate lesion.

Highlights

Middle ear glandular neoplasms are seldom the source of a middle ear mass
He designated these tumours as middle ear adenomas (MEA)
The post-operative course was uneventful and facial function improved to HB grade IV. This was only maintained for 3 months, when her facial function deteriorated again to grade HB VI, a repeat MRI scan Figure 4 revealed a tumour in the deep lobe of right parotid gland 13 mm in diameter and radiologically separate from the original tumour

Summary

Introduction

Middle ear glandular neoplasms are seldom the source of a middle ear mass. Hyams [1] was the first to describe. How to cite this paper: Mahrous, A.K., et al (2014) Isolated Adenoma with Neuroendocrine Differentiation Involving Both the Facial Nerve and Parotid Gland. He designated these tumours as middle ear adenomas (MEA). In 1980, Murphy et al [2] described a similar, if not identical, tumour and designated it a carcinoid tumour because of the ultrastructural evidence of neuroendocrine differentiation. This is a unique clinical scenario and to our knowledge, it has not been reported in the literature before

Case Report

Discussion

Summary