Abstract

Purpose: Numerous studies have demonstrated that, in women but not in men, lower quadriceps strength increases risk for radiographic and symptomatic knee OA, OA progression (JSN), and worsening self-reported physical function and physical performance. In addition, one case-control study revealed that thigh muscle strength predicted total knee arthroplasty (TKA) in women, but not in men followed for 12-60 months. The current study aimed to assess the extent to which lower risk for TKA in men and women over 84-month follow-up is associated with a) higher strength and b) lower antagonistic hamstring coactivation.

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