Abstract

the risk of hospitalization over the next year for those patients who had periprosthetic or femoral fracture in 2006-2007 as well as for subjects who did not have either type of fracture. Results: Among 58,521 Medicare beneficiaries who had elective primary THR in July 1995June 1996, 32,463 (55%) survived until January 2006. Over the next three years, 215 (0.7%) of these patients developed a periprosthetic proximal femoral fracture and 805 (2.5%) developed a femoral fracture unrelated to a prior implant. The annual incidence of periprosthetic fracture was 0.26/100 person-years and the annual incidence of femoral fracture was 0.96/100 person-years. Older age, female sex, white race and number of hospitalizations prior to fracture were associated with greater risk for femoral fracture, but not for periprosthetic fracture. The number of additional total hip or knee replacements from the index THR to the time of fracture was associatedwith periprosthetic fracture (see Table). Compared to those without fractures, THR recipients who sustained either type of fracture had four-fold higher risk of hospitalization in the subsequent year (36% vs. 9%, p<0.0001). Conclusions: Periprosthetic fractures do not share osteoporotic risk factors and occur less frequently than non-implant related femoral fractures, but they pose a similar burden of health care utilization. Due to the high prevalence of THR in older persons, these fractures lead to substantial resource use and morbidity.

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