Abstract
Isoflavones commonly found in plants such as soya and red clover express many health benefits including skin healing and anti-aging properties. The capacity to counteract aging is due to isoflavones being both anti-oxidants as well as phytoestrogens, hence preventing both extrinsic as well as intrinsic aging processes. In skincare formulations their effects could be enhanced with the aid of advanced delivery systems. Isoflavones from soya bean source has successfully been incorporated into liposomes and further used in commercially available anti-aging creams. However different plants vary in isoflavone composition. Red clover isoflavones express less affinity for the estrogen receptor whilst simultaneously containing isoflavone structures that should be easier to encapsulate in liposome vehicles compared to soya bean derived isoflavones. If liposome entrapped isoflavones could successfully be obtained, the novel liposome could have a visible effect on the skin and reduce the visible adverse outcomes of aging and moreover be advantageous in terms of endocrinological safety and/or have a higher efficiency of delivering active when compared to the currently available products on the market.
Highlights
Liposomes as Topical Delivery SystemsLiposomes are a versatile and prevalent vehicle for the delivery of actives in various cosmetic products
Liposomes are composed of lamellas of phospholipids or sphingolipids forming a spherical structure in an aqueous solution
The fatty-acids within the lamellas are comprised of a hydrophobic head group and a hydrophilic tail group
Summary
Isoflavones commonly found in plants such as soya and red clover expresses many health benefits including skin healing and anti-aging properties. The capacity to counteract aging is due to isoflavones being both anti-oxidants as well as phytoestrogens, preventing both extrinsic as well as intrinsic aging processes. In skincare formulations their effects could be enhanced with the aid of advanced delivery systems. Isoflavones from soya bean source has successfully been incorporated into liposomes and further used in commercially available anti-aging creams.
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