Abstract

AbstractSynthesis of 2‐amino‐3‐perfluoroalkylfurans has been accomplished by isocyanide‐based multicomponent reactions. Using methyl perfluoroalk‐2‐ynoates as the fluorinated build blocks in combination with isocyanides and aromatic aldehydes in one‐pot at room temperature, the perfluoroalkyl‐substituted 2‐aminofurans were obtained in good to excellent yields.

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