Year-end Sale % OFF 
Abstract
iSheep: an Integrated Resource for Sheep Genome, Variant and Phenotype.
Highlights
Sheep (Ovis aries), one of the main and oldest livestock in the world, are beneficial to human society by supplying wool, meat, milk, and skins
We collected whole-genome sequencing 26,802 genes annotated in the sheep genome, 1,417 breeds, and (WGS) data of 355 sheep, SNP BeadChip data of 2,423 sheep, 922 variant-trait associations from 52 publications
The results showed that the variants located in noncoding regions occupy the largest proportion (∼ 99.09%) of the genomes, whereas the variants located in coding regions such as synonymous and missense only account for no more than 1% (Supplementary Table 4)
Summary
Sheep (Ovis aries), one of the main and oldest livestock in the world, are beneficial to human society by supplying wool, meat, milk, and skins. The ISGC database consists of around 50 million filtered variants called using GATK and Samtools programs based on the reference genome assembly Oar_v3.1 It comprises the results at European Variation Archive (EVA) and the genotypes of several SNP chip arrays (Illumina 15K, 50K and HD 600K SNP chips). The EVA data set has gathered a large amount of genetic data, but the information on raw sequencing, annotation, breed and phenotype still remains underdeveloped. Another public database, dbSNP (https://www.ncbi.nlm.nih.gov/ snp/), was established in 1999 by the National Center for Biotechnology Information (NCBI, https://www.ncbi.nlm.nih.gov/), which has collected variation information of Homo sapiens, Mus musculus and other species (Sherry et al, 2001). Up to 2021, the latest version of GVM has included 355 generation sequencing (NGS) deposits of wild and domestic sheep (Li et al, 2021), which is a large data set, but lacks functional genetic variants and related information
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
