Abstract
4 cases of myocardial infarction, 2 of Summary them fatal, were observed in a series of 15 patients, aged 30-44, with nephrotic syndrome due to glomerulonephritis. All had longstanding nephrotic syndrome with hyperlipæmia, and only 1 had hypertension. Ischaemic heart-disease is a common complication of nephrotic syndrome, occurring with a frequency 85 times greater than in the general population of the same age-group. Every effort should be made to lower the plasma-lipid values to normal rapidly in nephrotic syndrome, and the measures should include vigorous use of steroids and immunosuppressive drugs.
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