Abstract
Objective: Ischemic stroke is the third leading cause of mortality in low income countries. The main aim of this study was to determine the rate and predictors of in-hospital mortality due to ischemic stroke in the Makwalla health care center and the University of Abuja Nigeria. Design and method: The study was Conducted from April 2019-May 2021 at the Makwalla health care center and the University of Abuja Teaching hospital. A census using restrospective cohort study design was conducted on medical records of adult patients with the diagnosis of ischemic attending the medical inpatient ward of the health facilities between November 2017 and September 2020. Cox hazard regression was used to determine the predictors of hospital Mortality. A two sided statistical test at 5% level of significance was used. Results: The main (+SD) duration of hospital stay was 11.5(10.04) days of total 208 patients 26(12.5%) Patients died in the hospital. Cox regression revealed that only a decrease in renal function particularly elevated serum creatinine (AHR = 8.848,95% CI:1:616-67.437) was associated with a statistically significant increase of in-hospital mortality. The symptom onset to admission time varied greatly among patients and ranged from 1 hour to 168 hours. Conclusions: The in hospital Mortality associated Ischemic stroke found to be high . Mainly elevation serum creatinine was highly associated with poorer out come in terms of in-hospital morality. Much work should be done on improving the knowledge and awareness of the community regarding ischemic stroke and stroke in general to encourage early medical seeking behavior and reduce mortality and long term disability.
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