Abstract
Glucokinase (GK) plays a key role in the control of blood glucose homeostasis. In the present study, we investigated the effect of ischemic preconditioning (IPC) on immunoreactivities of GK and its regulatory protein (GKRP) following 5 min of transient cerebral ischemia in gerbils.
Highlights
Introduction and objectivesGlucokinase (GK) plays a key role in the control of blood glucose homeostasis
We investigated the effect of ischemic preconditioning (IPC) on immunoreactivities of GK and its regulatory protein (GKRP) following 5 min of transient cerebral ischemia in gerbils
The gerbils were randomly assigned to 4 groups (shamoperated-group, ischemia-operated-group, IPC plus (+) sham-operated-group and IPC+ischemia-operatedgroup)
Summary
Introduction and objectivesGlucokinase (GK) plays a key role in the control of blood glucose homeostasis. Ischemic preconditioning maintains immunoreactivities of glucokinase and glucokinase regulatory protein in neurons of the gerbil hippocampal CA1 region following transient cerebral ischemia
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