Abstract
Single fiber electromyography has been used to study the influence of ischemia on the impulse transmission to individual muscle fibers in man. The jitter (the variability in time interval between the action potentials from 2 muscle fibers belonging to the same motor unit) has been used to study the neuro-muscular transmission in individual motor end-plates. Ischemia increased the jitter and caused more and more frequent blocking of the neuromuscular transmission until total block occurred. About 3,500–7,000 impulses could be transmitted before total block developed. When circulation was restored, the formerly blocked potential reappeared within seconds and the jitter was normal within some minutes, even if ischemia had lasted for 30 min.
Published Version
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