Abstract

Acute myocardial ischaemia causes increased production of oxygen free radicals 1, which may react with cellular membrane lipids causing lipid peroxidation2. Intrinsic antioxidant enzymes such as, superoxide dismutase (SOD) and glutathione peroxidase (GPx) may protect cellular integrity from oxygen free radicals3. In addition preconditioning (IPC) of the myocardium, has been proved useful in reducing ischaemic and reperfusion injury4.

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