Abstract

Is Transfusion an Independent Predictive Risk Factor of Postoperative Outcome in Pediatric Orthopedic Surgical Patients? A Retrospective Study

Highlights

  • Independent risk factors in studies concerning pediatric cardiac surgery and critical care patients [1,2,3]. This present study was undertaken to determine whether transfusion was an independent morbidity risk factor in pediatric orthopedic patients

  • The primary endpoint was to identify factors related to morbidity and the secondary endpoint was to identify factors related to length of stay in the intensive care unit (LOSICU), length of stay in hospital (LOSHOSP), total length of stay in hospital and duration of mechanical ventilation (LMV)in this pediatric population

  • Inclusion criteria consisted of patients admitted retrospectively for orthopedic surgery and who received blood products [packed red blood cells (PRBC) and/or fresh frozen plasma (FFP) and/ or concentrated platelet units (CPU)] in the intraoperative period and patients admitted for the same surgical speciality and who did not receive any blood transfusion during surgery orin the postoperative period

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Summary

Introduction

In pediatric patients admitted for surgery under anesthesia, morbi-mortality is related to mutiple factors. Several morbi-mortality risk factors have been identified of which transfusion is one of the. The local Transfusion Department provided a list of patients who had been transfused in the operation theatre from 1 January 2014 until 31 December 2016. We used the operation theatre programmation system (IPOP) to identify patients who did not receive blood products intraoperatively and postoperatively. 656 patients were identified from 1 January 2014 until May 2017 and 100 were included in the no transfusion group; these patients had similar characteristics and interventions whenever possible as those in the transfusion group (Figure 1). Intraoperative and postoperative morbi-mortality factors are multiple in pediatric patients. Studies in pediatric cardiac surgery and intensive care patients have identified transfusion as one independent factor among others

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