Abstract
Total knee replacement (TKR) comprises a significant, growing aspect in the management of patients with advanced arthritis of the knee for which conservative medical therapy has failed. Obesity, a rising epidemic, is considered an important independent risk factor in the development of osteoarthritis (OA). An aging population and increasing incidence of obesity contribute to a higher prevalence of OA and a subsequent greater need for TKR. The numbers of morbidly obese (MO) people undergoing TKR has consistently been rising. However, there have been concerns among patients and surgeons about the outcomes and complications of TKR in MO patients, especially given the morbidities associated with obesity. The goal of this systematic review was to assess relevant, up-to-date data on the safety, outcomes, and complications associated with TKR in MO patients.
Highlights
Total knee replacement (TKR) constitutes a significant development in the management of patients with advanced arthritis of the knee for which conservative medical therapy has failed
Primary TKR is more widespread among patients who are obese compared to patients who are considered to have a normal body mass index (BMI) [7]
Unicompartmental knee arthroplasty was excluded from the search results, which led to the exclusion of six studies
Summary
Total knee replacement (TKR) constitutes a significant development in the management of patients with advanced arthritis of the knee for which conservative medical therapy has failed. Obesity is a global problem and affects nearly a third of the population in the United States and the United Kingdom [2] It is a rising epidemic and one of the major public health problems [2]. The World Health Organization (WHO) stated that 500 million of the world's population were obese [2]. Both the aging population and the increase in obesity contribute to a higher prevalence of OA and a proportionally greater need for TKR [3].
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