Abstract

Abstract. From 1997 to 1999 1005 new born German Holstein calves were investigated for the incidence of supernumerary teats. Age at inspection varied from 1 to 4 weeks. In total 110 affected calves (20 male and 90 female) and their 21 sires were genotyped for five chromosome 3 microsatellites. The average size of half-sib families was 5.2 ranging from 2 to 17. A non-parametric multipoint linkage analysis showed no evidence for linkage.

Highlights

  • The occurrence of supernumerary teats has ben observed in several species

  • The pattern of penetrance must either be more complex, if a single gene is responsible for the trait (BRKA et al, 2000) or the inheritance is oligo- or polygenic

  • It can be expected that mapping experiments may add new insights into the genetics of bovine hyperthelia

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Summary

Introduction

The occurrence of supernumerary teats (hyperthelia) has ben observed in several species. In humans (URBANI and BETTI, 1996), sheep (VAINIKAINEN, 1945), guinea pigs (GOERTZEN and IBSEN, 1951), and mice (HOWARD and GUSTERSON, 2000) single gene dominant/recessive inheritance seems to be likely. The pattern of penetrance must either be more complex, if a single gene is responsible for the trait (BRKA et al, 2000) or the inheritance is oligo- or polygenic. It can be expected that mapping experiments may add new insights into the genetics of bovine hyperthelia. A second experiment (manuscript in preparation) showed weak evidence for linkage on BTA3. The aim of this study was to verify this result with independent families by genotyping affected half-sibs and their sires for five BTA3 microsatellite markers

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