Is There Association between Vitamin D Concentrations and Body Mass Index Variation in Women Submitted to Y-Roux Surgery?

Maria Tereza A Dos Santos,Fabiola Isabel Suano-Souza,Fernando Luiz Affonso Fonseca,Roseli Oselka Saccardo Sarni,Marise Lazaretti-Castro

doi:10.1155/2018/3251675

Maria Tereza A Dos Santos, Fabiola Isabel Suano-Souza + Show 3 more

Open Access

https://doi.org/10.1155/2018/3251675

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Abstract

Objective To evaluate vitamin D deficiency and body composition of women submitted to bariatric surgery and relate their body mass index variation after surgery to 25(OH)D concentrations. Method A cross-sectional and controlled study was performed including 49 obese adult volunteer women, submitted to Roux-en-Y gastric bypass (RYGB group). Collected Data Body mass index (BMI), self-declared ethnicity, economic condition, physical activity level, serum concentrations of 25-hydroxycholecalciferol (25(OH)D; radioimmunoassay), parathormone, and body composition by dual-energy X-ray absorptiometry (Hologic DXA-QDR-1000) were collected. Results 25(OH)D deficiency was found in 27 (55.1%) and 8 (21.1%) in the RYGB and control groups (p=0.002). Secondary hyperparathyroidism was more frequent in the RYGB group compared to the control group (15 (30.6%) versus 1 (2.6%); p=0.001). There was no relation of the studied variables and body composition with 25(OH)D deficiency. 25(OH)D concentrations were correlated (r=−0.531; p < 0.001) with BMI reduction, regardless of vitamin D supplementation. Conclusion Women submitted to bariatric surgery (RYGB) around three years ago had higher BMI and vitamin D deficiency, along with hyperparathyroidism, compared to the control group. There was no association between variables related to body composition and 25(OH)D concentrations. On the other hand, vitamin concentrations correlated negatively to BMI variation after undergoing surgery.

Highlights

Obesity, a chronic illness with a complex treatment, is a serious public health issue that affects millions of people all over the world
We aim to evaluate 25(OH)D deficiency and the body composition of women who were subjected to bariatric surgery and relate the variation of Body mass index (BMI) after surgery to 25(OH)D concentrations
In the group of women submitted to RYGB, the average age was 45.0 ± 9.0 years and the time after surgery was 3.3 ± 1.1 years. e average weight loss was 46.9 ± 16.4 kg and BMI reduction was 30.7 ± 4.7 kg/m2

Summary

Introduction

A chronic illness with a complex treatment, is a serious public health issue that affects millions of people all over the world. Regarding morbid obesity (BMI > 40 kg/m2) tendency on populational surveys carried out in Brazil since the 1970s, there was a 255% increase, going from 0.18% (in 1974–1975). Morbid obesity in Brazilian adults affects approximately 609,000 individuals, who would be possible candidates for bariatric surgery [3]. E number of bariatric surgeries performed in the country in the last 50 years has considerably increased since it is one of the most sustainable weight loss methods for morbidly obese people so far. Between 2001 and 2014, 49,425 bariatric surgeries were performed by the Unified Health System (SUS) [4]. Monitoring the nutritional condition, body composition, and dietary intake of these patients in the short- and long-term is fundamental for planning interventions, health

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